Our immune system is like a security checkpoint that scans our bodies’ cells to protect us from things that are harmful. Once detected, abnormal cells are attacked and removed by T-cells. A molecule found on the surface of cancer cells, PD-L1 functions as a disguise that allows cancer cells to go undetected. Dr Dan Chen explains how cancer immunotherapy may affect the PD-L1 pathway, enabling the body’s immune system to better detect, fight and kill cancer cells.
Just like normal cells, cancer cells have ways of repairing damage that occurs to them. In this episode of Science Illustrated we discuss one way, scientists are able to attack some cancers by preventing cancer cells from repairing themselves.